Rutile-TiO2/PtO2 Glass Coatings Disinfects Aquatic Legionella pneumophila via Morphology Change and Endotoxin Degradation under LED Irradiation

Legionella pneumophila (L. pneumophila) is the causative agent of Legionnaires’ disease and Pontiac fever, collectively known as legionellosis. L. infection occurs through inhalation contaminated aerosols from water systems in workplaces institutions. The development disinfectants that can eliminate such without evacuating people needed to prevent spread pneumophila. Photocatalysts are attractive do not harm human health. In particular, TiO2 photocatalyst kills under various conditions, but its mode action unknown. Here, we confirmed high performance containing PtO2 via degradation methylene blue (half-value period: 19.2 min) bactericidal activity against Escherichia coli 15.1 water. Using transmission electron microscopy, demonstrate disinfection 6.7 by accompanied remarkable cellular membrane internal damage Assays with limulus amebocyte lysate silver staining showed release endotoxin due photocatalytic this endotoxin. This first study mechanisms photocatalyst, namely, morphological changes Our results suggest might be effective controlling